A novel antifungal antibiotic, FR-900848. I. Production, isolation, physico-chemical and biological properties.

نویسندگان

  • M Yoshida
  • M Ezaki
  • M Hashimoto
  • M Yamashita
  • N Shigematsu
  • M Okuhara
  • M Kohsaka
  • K Horikoshi
چکیده

Streptoverticillium fervens produced a new antibiotic, FR-900848, which has a high specific activity against filamentous fungi. Purified by solvent extraction and column chromatography, the compound appears as colorless crystals. Its structure is C32H43N3O6, which consists of 5'-amino-5'-deoxy-5,6-dihydrouridine with an unsaturated fatty acid having unprecedented four serial and one isolated cyclopropane rings.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 43 7  شماره 

صفحات  -

تاریخ انتشار 1990